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The Regulatory Role of KIBRA and PTPN14 in Hippo Signaling and Beyond

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. Pivotal effectors of this pathway are YAP/TAZ, transcriptional co-activators whose dysfunction contributes to the development of cancer. Complex networks o...

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Detalles Bibliográficos
Autores principales: Wilson, Kayla E., Yang, Nuo, Mussell, Ashley L., Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929422/
https://www.ncbi.nlm.nih.gov/pubmed/27240404
http://dx.doi.org/10.3390/genes7060023