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Insights into the Stress Response Triggered by Kasugamycin in Escherichia coli

The bacteriostatic aminoglycoside antibiotic kasugamycin inhibits protein synthesis at an initial step without affecting translation elongation. It binds to the mRNA track of the ribosome and prevents formation of the translation initiation complex on canonical mRNAs. In contrast, translation of lea...

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Detalles Bibliográficos
Autores principales: Müller, Christian, Sokol, Lena, Vesper, Oliver, Sauert, Martina, Moll, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929434/
https://www.ncbi.nlm.nih.gov/pubmed/27258317
http://dx.doi.org/10.3390/antibiotics5020019