Inhibition of hypoxia inducible factor-1α attenuates abdominal aortic aneurysm progression through the down-regulation of matrix metalloproteinases

Hypoxia inducible factor-1α (HIF-1α) pathway is associated with many vascular diseases, including atherosclerosis, arterial aneurysms, pulmonary hypertension and chronic venous diseases. Significant HIF-1α expression could be found at the rupture edge at human abdominal aortic aneurysm (AAA) tissues...

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Detalles Bibliográficos
Autores principales: Tsai, Shih-Hung, Huang, Po-Hsun, Hsu, Yu-Juei, Peng, Yi-Jen, Lee, Chien-Hsing, Wang, Jen-Chun, Chen, Jaw-Wen, Lin, Shing-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929442/
https://www.ncbi.nlm.nih.gov/pubmed/27363580
http://dx.doi.org/10.1038/srep28612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929442/
https://www.ncbi.nlm.nih.gov/pubmed/27363580
http://dx.doi.org/10.1038/srep28612

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