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miR-2861 acts as a tumor suppressor via targeting EGFR/AKT2/CCND1 pathway in cervical cancer induced by human papillomavirus virus 16 E6

Persistent infection with oncogenic human papillomavirus viruses (HPVs) is a casual factor for cervical cancer and its precursors, and the abnormal constitutive expression of viral oncoprotein E6 is a key event during the malignant transformation. Here, we performed miRNA microarray to identify chan...

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Detalles Bibliográficos
Autores principales: Xu, Junfen, Wan, Xiaoyun, Chen, Xiaojing, Fang, Yifeng, Cheng, Xiaodong, Xie, Xing, Lu, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929448/
https://www.ncbi.nlm.nih.gov/pubmed/27364926
http://dx.doi.org/10.1038/srep28968