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Alignment-free microbial phylogenomics under scenarios of sequence divergence, genome rearrangement and lateral genetic transfer

Alignment-free (AF) approaches have recently been highlighted as alternatives to methods based on multiple sequence alignment in phylogenetic inference. However, the sensitivity of AF methods to genome-scale evolutionary scenarios is little known. Here, using simulated microbial genome data we syste...

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Detalles Bibliográficos
Autores principales: Bernard, Guillaume, Chan, Cheong Xin, Ragan, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929450/
https://www.ncbi.nlm.nih.gov/pubmed/27363362
http://dx.doi.org/10.1038/srep28970