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Polysaccharide Nanoparticles for Efficient siRNA Targeting in Cancer Cells by Supramolecular pK(a) Shift
Biomacromolecular pK(a) shifting is considered as one of the most ubiquitous processes in biochemical events, e.g., the enzyme-catalyzed reaction and protein conformational stabilization. In this paper, we report on the construction of biocompatible polysaccharide nanoparticle with targeting ability...
Autores principales: | Zhang, Ying-Ming, Yang, Yang, Zhang, Yu-Hui, Liu, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929451/ https://www.ncbi.nlm.nih.gov/pubmed/27363811 http://dx.doi.org/10.1038/srep28848 |
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