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Inhibition of HIV-1 reactivation by a telomerase-derived peptide in a HSP90-dependent manner

A peptide vaccine designed to induce T-cell immunity to telomerase, GV1001, has been shown to modulate cellular signaling pathways and confer a direct anti-cancer effect through the interaction with heat shock protein (HSP) 90 and 70. Here, we have found that GV1001 can modulate transactivation prot...

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Detalles Bibliográficos
Autores principales: Kim, Hong, Choi, Myung-Soo, Inn, Kyung-Soo, Kim, Bum-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929463/
https://www.ncbi.nlm.nih.gov/pubmed/27363520
http://dx.doi.org/10.1038/srep28896