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Inhibition of HIV-1 reactivation by a telomerase-derived peptide in a HSP90-dependent manner
A peptide vaccine designed to induce T-cell immunity to telomerase, GV1001, has been shown to modulate cellular signaling pathways and confer a direct anti-cancer effect through the interaction with heat shock protein (HSP) 90 and 70. Here, we have found that GV1001 can modulate transactivation prot...
Autores principales: | Kim, Hong, Choi, Myung-Soo, Inn, Kyung-Soo, Kim, Bum-Joon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929463/ https://www.ncbi.nlm.nih.gov/pubmed/27363520 http://dx.doi.org/10.1038/srep28896 |
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