Visualization of Neuregulin 1 ectodomain shedding reveals its local processing in vitro and in vivo

Neuregulin1 (NRG1) plays diverse developmental roles and is likely involved in several neurological disorders including schizophrenia. The transmembrane NRG1 protein is proteolytically cleaved and released as a soluble ligand for ErbB receptors. Such post-translational processing, referred to as ‘ec...

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Detalles Bibliográficos
Autores principales: Kamezaki, Aosa, Sato, Fuminori, Aoki, Kazuhiro, Asakawa, Kazuhide, Kawakami, Koichi, Matsuzaki, Fumio, Sehara-Fujisawa, Atsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929465/
https://www.ncbi.nlm.nih.gov/pubmed/27364328
http://dx.doi.org/10.1038/srep28873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929465/
https://www.ncbi.nlm.nih.gov/pubmed/27364328
http://dx.doi.org/10.1038/srep28873

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