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Tumour-suppression function of KLF12 through regulation of anoikis

Suppression of detachment-induced cell death, known as anoikis, is an essential step for cancer metastasis to occur. We report here that expression of KLF12, a member of the Kruppel-like family of transcription factors, is downregulated in lung cancer cell lines that have been selected to grow in th...

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Detalles Bibliográficos
Autores principales: Godin-Heymann, N, Brabetz, S, Murillo, M M, Saponaro, M, Santos, C R, Lobley, A, East, P, Chakravarty, P, Matthews, N, Kelly, G, Jordan, S, Castellano, E, Downward, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929484/
https://www.ncbi.nlm.nih.gov/pubmed/26455320
http://dx.doi.org/10.1038/onc.2015.394