11β-Hydroxysteroid Dehydrogenase Type 1 Is Expressed in Neutrophils and Restrains an Inflammatory Response in Male Mice

Endogenous glucocorticoid action within cells is enhanced by prereceptor metabolism by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which converts intrinsically inert cortisone and 11-dehydrocorticosterone into active cortisol and corticosterone, respectively. 11β-HSD1 is highly expressed in...

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Detalles Bibliográficos
Autores principales: Coutinho, Agnes E., Kipari, Tiina M. J., Zhang, Zhenguang, Esteves, Cristina L., Lucas, Christopher D., Gilmour, James S., Webster, Scott P., Walker, Brian R., Hughes, Jeremy, Savill, John S., Seckl, Jonathan R., Rossi, Adriano G., Chapman, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929552/
https://www.ncbi.nlm.nih.gov/pubmed/27145012
http://dx.doi.org/10.1210/en.2016-1118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929552/
https://www.ncbi.nlm.nih.gov/pubmed/27145012
http://dx.doi.org/10.1210/en.2016-1118

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