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Optimal numbers of residues in linkers of DNA polymerase I, T7 primase and DNA polymerase IV

DNA polymerase I (PolI), T7 primase and DNA polymerase IV (Dpo4) have a common feature in their structures that the two main domains are connected by an unstructured polypeptide linker. To perform their specific enzymatic activities, the enzymes are required to rearrange the position and orientation...

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Detalles Bibliográficos
Autores principales: Fu, Yi-Ben, Wang, Zhan-Feng, Wang, Peng-Ye, Xie, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929570/
https://www.ncbi.nlm.nih.gov/pubmed/27364863
http://dx.doi.org/10.1038/srep29125