Slug inhibits pancreatic cancer initiation by blocking Kras-induced acinar-ductal metaplasia

Cells in the pancreas that have undergone acinar-ductal metaplasia (ADM) can transform into premalignant cells that can eventually become cancerous. Although the epithelial-mesenchymal transition regulator Snail (Snai1) can cooperate with Kras in acinar cells to enhance ADM development, the contribu...

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Detalles Bibliográficos
Autores principales: Ebine, Kazumi, Chow, Christina R., DeCant, Brian T., Hattaway, Holly Z., Grippo, Paul J., Kumar, Krishan, Munshi, Hidayatullah G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929679/
https://www.ncbi.nlm.nih.gov/pubmed/27364947
http://dx.doi.org/10.1038/srep29133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929679/
https://www.ncbi.nlm.nih.gov/pubmed/27364947
http://dx.doi.org/10.1038/srep29133

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