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Slug inhibits pancreatic cancer initiation by blocking Kras-induced acinar-ductal metaplasia

Cells in the pancreas that have undergone acinar-ductal metaplasia (ADM) can transform into premalignant cells that can eventually become cancerous. Although the epithelial-mesenchymal transition regulator Snail (Snai1) can cooperate with Kras in acinar cells to enhance ADM development, the contribu...

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Detalles Bibliográficos
Autores principales:	Ebine, Kazumi, Chow, Christina R., DeCant, Brian T., Hattaway, Holly Z., Grippo, Paul J., Kumar, Krishan, Munshi, Hidayatullah G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929679/ https://www.ncbi.nlm.nih.gov/pubmed/27364947 http://dx.doi.org/10.1038/srep29133

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