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In vitro effects of platelet-rich gel supernatants on histology and chondrocyte apoptosis scores, hyaluronan release and gene expression of equine cartilage explants challenged with lipopolysaccharide

BACKGROUND: Platelet-rich plasma (PRP) preparations are a common treatment in equine osteoarthritis (OA). However, there are controversies regarding the ideal concentration of platelets and leukocytes in these biological substances necessary to induce an adequate anti-inflammatory and anabolic respo...

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Detalles Bibliográficos
Autores principales: Carmona, Jorge U., Ríos, Diana L., López, Catalina, Álvarez, María E., Pérez, Jorge E., Bohórquez, Mabel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929746/
https://www.ncbi.nlm.nih.gov/pubmed/27369779
http://dx.doi.org/10.1186/s12917-016-0759-8