A next generation sequencing-based method to study the intra-host genetic diversity of norovirus in patients with acute and chronic infection

BACKGROUND: Immunocompromised individuals with chronic norovirus (NoV) infection and elderly patients are hypothesized to be reservoirs where NoV might accumulate mutations and evolve into pandemic strains. Next generation sequencing (NGS) methods can monitor the intra-host diversity of NoV and its...

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Detalles Bibliográficos
Autores principales: Hasing, Maria E., Hazes, Bart, Lee, Bonita E., Preiksaitis, Jutta K., Pang, Xiaoli L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929757/
https://www.ncbi.nlm.nih.gov/pubmed/27363999
http://dx.doi.org/10.1186/s12864-016-2831-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929757/
https://www.ncbi.nlm.nih.gov/pubmed/27363999
http://dx.doi.org/10.1186/s12864-016-2831-y

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