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Major influence of CD4 count at the initiation of cART on viral and immunological reservoir constitution in HIV-1 infected patients

BACKGROUND: A persistent immune activation is observed in gut during HIV-1 infection, which is not completely reversed by a combined antiretroviral therapy (cART). The impact of the time of cART initiation may highly influence the size of the viral reservoir and the ratio of CD4(+)/CD8(+) T cells in...

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Detalles Bibliográficos
Autores principales: Depincé-Berger, Anne-Emmanuelle, Vergnon-Miszczycha, Delphine, Girard, Alexandre, Frésard, Anne, Botelho-Nevers, Elisabeth, Lambert, Claude, Del Tedesco, Emilie, Genin, Christian, Pozzetto, Bruno, Lucht, Frédéric, Roblin, Xavier, Bourlet, Thomas, Paul, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929778/
https://www.ncbi.nlm.nih.gov/pubmed/27363286
http://dx.doi.org/10.1186/s12977-016-0278-5