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Major influence of CD4 count at the initiation of cART on viral and immunological reservoir constitution in HIV-1 infected patients
BACKGROUND: A persistent immune activation is observed in gut during HIV-1 infection, which is not completely reversed by a combined antiretroviral therapy (cART). The impact of the time of cART initiation may highly influence the size of the viral reservoir and the ratio of CD4(+)/CD8(+) T cells in...
Autores principales: | Depincé-Berger, Anne-Emmanuelle, Vergnon-Miszczycha, Delphine, Girard, Alexandre, Frésard, Anne, Botelho-Nevers, Elisabeth, Lambert, Claude, Del Tedesco, Emilie, Genin, Christian, Pozzetto, Bruno, Lucht, Frédéric, Roblin, Xavier, Bourlet, Thomas, Paul, Stéphane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929778/ https://www.ncbi.nlm.nih.gov/pubmed/27363286 http://dx.doi.org/10.1186/s12977-016-0278-5 |
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