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Application of a delta-6 desaturase with α-linolenic acid preference on eicosapentaenoic acid production in Mortierella alpina

BACKGROUND: Delta-6 desaturase (FADS6) is a key bifunctional enzyme desaturating linoleic acid (LA) or α-linolenic acid (ALA) in the biosynthesis of polyunsaturated fatty acids (PUFAs). In previous work, we analyzed the substrate specificity of two FADS6 enzymes from Mortierella alpina ATCC 32222 (M...

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Detalles Bibliográficos
Autores principales: Shi, Haisu, Chen, Haiqin, Gu, Zhennan, Zhang, Hao, Chen, Wei, Chen, Yong Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929779/
https://www.ncbi.nlm.nih.gov/pubmed/27364006
http://dx.doi.org/10.1186/s12934-016-0516-5