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Elevated Glucose Oxidation, Reduced Insulin Secretion, and a Fatty Heart May Be Protective Adaptions in Ischemic CAD

BACKGROUND: Insulin resistance, β-cell dysfunction, and ectopic fat deposition have been implicated in the pathogenesis of coronary artery disease (CAD) and type 2 diabetes, which is common in CAD patients. We investigated whether CAD is an independent predictor of these metabolic abnormalities and...

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Detalles Bibliográficos
Autores principales: Hannukainen, J. C., Lautamäki, R., Mari, A., Pärkkä, J. P., Bucci, M., Guzzardi, M. A., Kajander, S., Tuokkola, T., Knuuti, J., Iozzo, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929844/
https://www.ncbi.nlm.nih.gov/pubmed/27045985
http://dx.doi.org/10.1210/jc.2015-4091