Cargando…

Increased genetic risk for obesity in premature coronary artery disease

There is ongoing controversy as to whether obesity confers risk for CAD independently of associated risk factors including diabetes mellitus. We have carried out a Mendelian randomization study using a genetic risk score (GRS) for body mass index (BMI) based on 35 risk alleles to investigate this qu...

Descripción completa

Detalles Bibliográficos
Autores principales: Cole, Christopher B, Nikpay, Majid, Stewart, Alexandre FR, McPherson, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929880/
https://www.ncbi.nlm.nih.gov/pubmed/26220701
http://dx.doi.org/10.1038/ejhg.2015.162