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Increased genetic risk for obesity in premature coronary artery disease
There is ongoing controversy as to whether obesity confers risk for CAD independently of associated risk factors including diabetes mellitus. We have carried out a Mendelian randomization study using a genetic risk score (GRS) for body mass index (BMI) based on 35 risk alleles to investigate this qu...
Autores principales: | Cole, Christopher B, Nikpay, Majid, Stewart, Alexandre FR, McPherson, Ruth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929880/ https://www.ncbi.nlm.nih.gov/pubmed/26220701 http://dx.doi.org/10.1038/ejhg.2015.162 |
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