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Absence of systemic oxidative stress and increased CSF prostaglandin F(2α) in progressive MS
OBJECTIVE: We aimed to investigate the role of oxidative stress in the progression of multiple sclerosis (MS). METHODS: We determined by liquid chromatography–tandem mass spectrometry nonenzymatic (F(2)-isoprostanes) and enzymatic oxidation products of arachidonic acid (prostaglandin F(2α) [PGF(2α)]...
Autores principales: | Lam, Magda A., Maghzal, Ghassan J., Khademi, Mohsen, Piehl, Fredik, Ratzer, Rikke, Romme Christensen, Jeppe, Sellebjerg, Finn Thorup, Olsson, Tomas, Stocker, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929888/ https://www.ncbi.nlm.nih.gov/pubmed/27386506 http://dx.doi.org/10.1212/NXI.0000000000000256 |
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