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Isoform-specific modulation of the chemical sensitivity of conserved TRPA1 channel in the major honeybee ectoparasitic mite, Tropilaelaps mercedesae

We identified and characterized the TRPA1 channel of Tropilaelaps mercedesae (TmTRPA1), one of two major species of honeybee ectoparasitic mite. Three TmTRPA1 isoforms with unique N-terminal sequences were activated by heat, and the isoform highly expressed in the mite's front legs, TmTRPA1b, w...

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Detalles Bibliográficos
Autores principales: Dong, Xiaofeng, Kashio, Makiko, Peng, Guangda, Wang, Xinyue, Tominaga, Makoto, Kadowaki, Tatsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929936/
https://www.ncbi.nlm.nih.gov/pubmed/27307515
http://dx.doi.org/10.1098/rsob.160042