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Structural and biochemical analyses of monoubiquitinated human histones H2B and H4

Monoubiquitination is a major histone post-translational modification. In humans, the histone H2B K120 and histone H4 K31 residues are monoubiquitinated and may form transcriptionally active chromatin. In this study, we reconstituted nucleosomes containing H2B monoubiquitinated at position 120 (H2Bu...

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Detalles Bibliográficos
Autores principales: Machida, Shinichi, Sekine, Satoshi, Nishiyama, Yuuki, Horikoshi, Naoki, Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929944/
https://www.ncbi.nlm.nih.gov/pubmed/27335322
http://dx.doi.org/10.1098/rsob.160090