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Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars

Mycobacterium tuberculosis (Mtb), the aetiological agent of tuberculosis, has evolved to scavenge nutrients from the confined environment of host macrophages with mycobacterial ATP-binding cassette (ABC) transporters playing a key role in nutrient acquisition. Mtb-UspC (Rv2318) is the solute-binding...

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Detalles Bibliográficos
Autores principales: Fullam, Elizabeth, Prokes, Ivan, Fütterer, Klaus, Besra, Gurdyal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929945/
https://www.ncbi.nlm.nih.gov/pubmed/27335320
http://dx.doi.org/10.1098/rsob.160105