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CCL5 activation of CCR5 regulates cell metabolism to enhance proliferation of breast cancer cells

In earlier studies, we showed that CCL5 enhances proliferation and survival of MCF-7 breast cancer cells in an mTOR-dependent manner and we provided evidence that, for T cells, CCL5 activation of CCR5 results in increased glycolysis and enhanced ATP production. Increases in metabolic activity of can...

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Detalles Bibliográficos
Autores principales: Gao, Darrin, Rahbar, Ramtin, Fish, Eleanor N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929946/
https://www.ncbi.nlm.nih.gov/pubmed/27335323
http://dx.doi.org/10.1098/rsob.160122