Increased abundance of translation machinery in stem cell–derived neural progenitor cells from four schizophrenia patients

The genetic and epigenetic factors contributing to risk for schizophrenia (SZ) remain unresolved. Here we demonstrate, for the first time, perturbed global protein translation in human-induced pluripotent stem cell (hiPSC)-derived forebrain neural progenitor cells (NPCs) from four SZ patients relati...

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Detalles Bibliográficos
Autores principales: Topol, A, English, J A, Flaherty, E, Rajarajan, P, Hartley, B J, Gupta, S, Desland, F, Zhu, S, Goff, T, Friedman, L, Rapoport, J, Felsenfeld, D, Cagney, G, Mackay-Sim, A, Savas, J N, Aronow, B, Fang, G, Zhang, B, Cotter, D, Brennand, K J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930118/
https://www.ncbi.nlm.nih.gov/pubmed/26485546
http://dx.doi.org/10.1038/tp.2015.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930118/
https://www.ncbi.nlm.nih.gov/pubmed/26485546
http://dx.doi.org/10.1038/tp.2015.118

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