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BDNF–TrkB signaling in the nucleus accumbens shell of mice has key role in methamphetamine withdrawal symptoms

Depression is a core symptom of methamphetamine (METH) withdrawal during the first several weeks of abstinence. However, the precise mechanisms underlying METH withdrawal symptoms remain unknown. Brain-derived neurotrophic factor (BDNF) and its specific receptor, tropomyosin-related kinase (TrkB), h...

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Detalles Bibliográficos
Autores principales: Ren, Q, Ma, M, Yang, C, Zhang, J-C, Yao, W, Hashimoto, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930133/
https://www.ncbi.nlm.nih.gov/pubmed/26506052
http://dx.doi.org/10.1038/tp.2015.157