Cargando…

How Can Viral Dynamics Models Inform Endpoint Measures in Clinical Trials of Therapies for Acute Viral Infections?

Acute viral infections pose many practical challenges for the accurate assessment of the impact of novel therapies on viral growth and decay. Using the example of influenza A, we illustrate how the measurement of infection-related quantities that determine the dynamics of viral load within the human...

Descripción completa

Detalles Bibliográficos
Autores principales: Vegvari, Carolin, Hadjichrysanthou, Christoforos, Cauët, Emilie, Lawrence, Emma, Cori, Anne, de Wolf, Frank, Anderson, Roy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930163/
https://www.ncbi.nlm.nih.gov/pubmed/27367230
http://dx.doi.org/10.1371/journal.pone.0158237