Fenretinide (4-HPR) Targets Caspase-9, ERK 1/2 and the Wnt3a/β-Catenin Pathway in Medulloblastoma Cells and Medulloblastoma Cell Spheroids

Medulloblastoma (MB), a neuroectodermal tumor arising in the cerebellum, represents the most frequent childhood brain malignancy. Current treatments for MB combine radiation and chemotherapy and are often associated with relevant side effects; novel therapeutic strategies are urgently needed. N-(4-H...

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Detalles Bibliográficos
Autores principales: Bassani, Barbara, Bartolini, Desirèe, Pagani, Arianna, Principi, Elisa, Zollo, Massimo, Noonan, Douglas M., Albini, Adriana, Bruno, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930187/
https://www.ncbi.nlm.nih.gov/pubmed/27367907
http://dx.doi.org/10.1371/journal.pone.0154111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930187/
https://www.ncbi.nlm.nih.gov/pubmed/27367907
http://dx.doi.org/10.1371/journal.pone.0154111

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