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Pharmacokinetic Interaction of Chrysin with Caffeine in Rats

Pharmacokinetic interaction of chrysin, a flavone present in honey, propolis and herbs, with caffeine was investigated in male Sprague-Dawley rats. Because chrysin inhibited CYP1A-selective ethoxyresorufin O-deethylase and methoxyresorufin O-demethylase activities in enriched rat liver microsomes, t...

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Detalles Bibliográficos
Autores principales: Noh, Keumhan, Oh, Do Gyeong, Nepal, Mahesh Raj, Jeong, Ki Sun, Choi, Yongjoo, Kang, Mi Jeong, Kang, Wonku, Jeong, Hye Gwang, Jeong, Tae Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930290/
https://www.ncbi.nlm.nih.gov/pubmed/27098862
http://dx.doi.org/10.4062/biomolther.2015.197