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Esophageal Submucosal Injection of Capsaicin but Not Acid Induces Symptoms in Normal Subjects

BACKGROUND/AIMS: Transient receptor potential vanilloid-1 (TRPV1) is a candidate for mediating acid-induced symptoms in the esophagus. We conducted studies to determine if the presence of acid in the mucosa/submucosa and direct activation of TRPV1 by capsaicin elicited symptoms in normal healthy sub...

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Detalles Bibliográficos
Autores principales: Lee, Robert H, Korsapati, Hariprasad, Bhalla, Vikas, Varki, Nissi, Mittal, Ravinder K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Neurogastroenterology and Motility 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930298/
https://www.ncbi.nlm.nih.gov/pubmed/26932896
http://dx.doi.org/10.5056/jnm15166