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miR-125b-1 is repressed by histone modifications in breast cancer cell lines

PURPOSE: Downregulation of miR-125b-1 is associated with poor prognosis in breast cancer patients. In this work we investigated the effect of histone modifications on the regulation of this gene promoter. METHODS AND RESULTS: We evaluated the enrichment of two histone modifications involved in gene...

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Detalles Bibliográficos
Autores principales: Cisneros-Soberanis, Fernanda, Andonegui, Marco A., Herrera, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930440/
https://www.ncbi.nlm.nih.gov/pubmed/27386402
http://dx.doi.org/10.1186/s40064-016-2475-z