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Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro

BACKGROUND: Nutrient excess underpins the development of nonalcoholic fatty liver disease (NAFLD). The ensuing metabolic derangement is characterised by increased cellular respiration, oxidative stress and mitochondrial impairment. We have previously recapitulated these events in an in vitro cellula...

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Detalles Bibliográficos
Autores principales: Lockman, Khalida Ann, Htun, Varanand, Sinha, Rohit, Treskes, Philipp, Nelson, Leonard J., Martin, Sarah F., Rogers, Sophie M., Le Bihan, Thierry, Hayes, Peter C., Plevris, John N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930558/
https://www.ncbi.nlm.nih.gov/pubmed/27368608
http://dx.doi.org/10.1186/s12944-016-0283-7