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Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro
BACKGROUND: Nutrient excess underpins the development of nonalcoholic fatty liver disease (NAFLD). The ensuing metabolic derangement is characterised by increased cellular respiration, oxidative stress and mitochondrial impairment. We have previously recapitulated these events in an in vitro cellula...
Autores principales: | Lockman, Khalida Ann, Htun, Varanand, Sinha, Rohit, Treskes, Philipp, Nelson, Leonard J., Martin, Sarah F., Rogers, Sophie M., Le Bihan, Thierry, Hayes, Peter C., Plevris, John N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930558/ https://www.ncbi.nlm.nih.gov/pubmed/27368608 http://dx.doi.org/10.1186/s12944-016-0283-7 |
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