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Investigation of allosteric coupling in human β(2)-adrenergic receptor in the presence of intracellular loop 3
BACKGROUND: This study investigates the allosteric coupling that exists between the intra- and extracellular parts of human β(2)-adrenergic receptor (β(2)-AR), in the presence of the intracellular loop 3 (ICL3), which is missing in all crystallographic experiments and most of the simulation studies...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930610/ https://www.ncbi.nlm.nih.gov/pubmed/27368374 http://dx.doi.org/10.1186/s12900-016-0061-9 |