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Determinants of FIV and HIV Vif sensitivity of feline APOBEC3 restriction factors

BACKGROUND: Feline immunodeficiency virus (FIV) is a global pathogen of Felidae species and a model system for Human immunodeficiency virus (HIV)-induced AIDS. In felids such as the domestic cat (Felis catus), APOBEC3 (A3) genes encode for single-domain A3Z2s, A3Z3 and double-domain A3Z2Z3 anti-vira...

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Detalles Bibliográficos
Autores principales: Zhang, Zeli, Gu, Qinyong, Jaguva Vasudevan, Ananda Ayyappan, Hain, Anika, Kloke, Björn-Philipp, Hasheminasab, Sascha, Mulnaes, Daniel, Sato, Kei, Cichutek, Klaus, Häussinger, Dieter, Bravo, Ignacio G., Smits, Sander H. J., Gohlke, Holger, Münk, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930625/
https://www.ncbi.nlm.nih.gov/pubmed/27368163
http://dx.doi.org/10.1186/s12977-016-0274-9