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Novel Insights into the Roles of Rho Kinase in Cancer

Rho-associated coiled-coil kinase (ROCK) is a major downstream effector of the small GTPase RhoA. The ROCK family, consisting of ROCK1 and ROCK2, plays a central role in the organization of the actin cytoskeleton, and is involved in a wide range of fundamental cellular functions such as contraction,...

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Detalles Bibliográficos
Autores principales: Wei, Lei, Surma, Michelle, Shi, Stephanie, Lambert-Cheatham, Nathan, Shi, Jianjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930737/
https://www.ncbi.nlm.nih.gov/pubmed/26725045
http://dx.doi.org/10.1007/s00005-015-0382-6