Cargando…

Sequestration of sorcin by aberrant forms of tau results in the defective calcium homeostasis

Neurofi brillary tangles (NFTs) of microtubule-associated protein tau are a pathological hallmark of Alzheimer's disease (AD). Endoplasmic reticulum (ER) stress has been known to be involved in the pathogenesis of AD. However, the exact role of ER stress in tau pathology has not yet been clearl...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Song-In, Lee, Hee Jae, Kim, Sung-Soo, Kwon, Yong-Soo, Chun, Wanjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930907/
https://www.ncbi.nlm.nih.gov/pubmed/27382355
http://dx.doi.org/10.4196/kjpp.2016.20.4.387