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Rapamycin‐induced autophagy sensitizes A549 cells to radiation associated with DNA damage repair inhibition

BACKGROUND: Autophagy has been reported to increase in cancer cells after radiation. However, it remains unknown whether increased autophagy as a result of radiation affects DNA damage repair and sensitizes cancer cells. In this study, the radiosensitization effect of rapamycin, a mammalian target o...

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Detalles Bibliográficos
Autores principales: Li, Yong, Liu, Fen, Wang, Yong, Li, Donghai, Guo, Fei, Xu, Liyao, Zeng, Zhengguo, Zhong, Xiaojun, Qian, Kejian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930955/
https://www.ncbi.nlm.nih.gov/pubmed/27385978
http://dx.doi.org/10.1111/1759-7714.12332