Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism

Small GTPases play a critical role in membrane traffic. Among them, Arf6 mediates transport to and from the plasma membrane, as well as phosphoinositide signalling and cholesterol homeostasis. Here we delineate the molecular basis for the link between Arf6 and cholesterol homeostasis using an induci...

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Detalles Bibliográficos
Autores principales: Marquer, Catherine, Tian, Huasong, Yi, Julie, Bastien, Jayson, Dall'Armi, Claudia, Yang-Klingler, YoungJoo, Zhou, Bowen, Chan, Robin Barry, Di Paolo, Gilbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931008/
https://www.ncbi.nlm.nih.gov/pubmed/27336679
http://dx.doi.org/10.1038/ncomms11919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931008/
https://www.ncbi.nlm.nih.gov/pubmed/27336679
http://dx.doi.org/10.1038/ncomms11919

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