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Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism
Small GTPases play a critical role in membrane traffic. Among them, Arf6 mediates transport to and from the plasma membrane, as well as phosphoinositide signalling and cholesterol homeostasis. Here we delineate the molecular basis for the link between Arf6 and cholesterol homeostasis using an induci...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931008/ https://www.ncbi.nlm.nih.gov/pubmed/27336679 http://dx.doi.org/10.1038/ncomms11919 |