Beta 1-integrin–c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes

Receptor tyrosine kinases (RTKs) and integrins cooperate to stimulate cell migration and tumour metastasis. Here we report that an integrin influences signalling of an RTK, c-Met, from inside the cell, to promote anchorage-independent cell survival. Thus, c-Met and β1-integrin co-internalize and bec...

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Detalles Bibliográficos
Autores principales: Barrow-McGee, Rachel, Kishi, Naoki, Joffre, Carine, Ménard, Ludovic, Hervieu, Alexia, Bakhouche, Bakhouche A., Noval, Alejandro J., Mai, Anja, Guzmán, Camilo, Robert-Masson, Luisa, Iturrioz, Xavier, Hulit, James, Brennan, Caroline H., Hart, Ian R., Parker, Peter J., Ivaska, Johanna, Kermorgant, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931016/
https://www.ncbi.nlm.nih.gov/pubmed/27336951
http://dx.doi.org/10.1038/ncomms11942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931016/
https://www.ncbi.nlm.nih.gov/pubmed/27336951
http://dx.doi.org/10.1038/ncomms11942

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