Cardiac sodium channel palmitoylation regulates channel availability and myocyte excitability with implications for arrhythmia generation

Cardiac voltage-gated sodium channels (Nav1.5) play an essential role in regulating cardiac electric activity by initiating and propagating action potentials in the heart. Altered Nav1.5 function is associated with multiple cardiac diseases including long-QT3 and Brugada syndrome. Here, we show that...

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Detalles Bibliográficos
Autores principales: Pei, Zifan, Xiao, Yucheng, Meng, Jingwei, Hudmon, Andy, Cummins, Theodore R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931030/
https://www.ncbi.nlm.nih.gov/pubmed/27337590
http://dx.doi.org/10.1038/ncomms12035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931030/
https://www.ncbi.nlm.nih.gov/pubmed/27337590
http://dx.doi.org/10.1038/ncomms12035

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