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Cardiac sodium channel palmitoylation regulates channel availability and myocyte excitability with implications for arrhythmia generation
Cardiac voltage-gated sodium channels (Nav1.5) play an essential role in regulating cardiac electric activity by initiating and propagating action potentials in the heart. Altered Nav1.5 function is associated with multiple cardiac diseases including long-QT3 and Brugada syndrome. Here, we show that...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931030/ https://www.ncbi.nlm.nih.gov/pubmed/27337590 http://dx.doi.org/10.1038/ncomms12035 |