MYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation

The circadian clock and the cell cycle are major cellular systems that organize global physiology in temporal fashion. It seems conceivable that the potentially conflicting programs are coordinated. We show here that overexpression of MYC in U2OS cells attenuates the clock and conversely promotes ce...

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Detalles Bibliográficos
Autores principales: Shostak, Anton, Ruppert, Bianca, Ha, Nati, Bruns, Philipp, Toprak, Umut H., Eils, Roland, Schlesner, Matthias, Diernfellner, Axel, Brunner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931031/
https://www.ncbi.nlm.nih.gov/pubmed/27339797
http://dx.doi.org/10.1038/ncomms11807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931031/
https://www.ncbi.nlm.nih.gov/pubmed/27339797
http://dx.doi.org/10.1038/ncomms11807

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