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A Modified NK Cell Degranulation Assay Applicable for Routine Evaluation of NK Cell Function

Natural killer (NK) cells play important role in innate immunity against tumors and viral infections. Studies show that lysosome-associated membrane protein-1 (LAMP-1, CD107a) is a marker for degranulation of NK and cytotoxic T cells and its expression is a sensitive marker for the cytotoxic activit...

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Detalles Bibliográficos
Autores principales: Shabrish, Snehal, Gupta, Maya, Madkaikar, Manisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931065/
https://www.ncbi.nlm.nih.gov/pubmed/27413758
http://dx.doi.org/10.1155/2016/3769590