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Structural basis for the antagonistic roles of RNP-8 and GLD-3 in GLD-2 poly(A)-polymerase activity

Cytoplasmic polyadenylation drives the translational activation of specific mRNAs in early metazoan development and is performed by distinct complexes that share the same catalytic poly(A)-polymerase subunit, GLD-2. The activity and specificity of GLD-2 depend on its binding partners. In Caenorhabdi...

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Detalles Bibliográficos
Autores principales: Nakel, Katharina, Bonneau, Fabien, Basquin, Claire, Habermann, Bianca, Eckmann, Christian R., Conti, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931106/
https://www.ncbi.nlm.nih.gov/pubmed/27288313
http://dx.doi.org/10.1261/rna.056598.116