Structural evidence for Nap1‐dependent H2A–H2B deposition and nucleosome assembly

Nap1 is a histone chaperone involved in the nuclear import of H2A–H2B and nucleosome assembly. Here, we report the crystal structure of Nap1 bound to H2A–H2B together with in vitro and in vivo functional studies that elucidate the principles underlying Nap1‐mediated H2A–H2B chaperoning and nucleosom...

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Detalles Bibliográficos
Autores principales: Aguilar‐Gurrieri, Carmen, Larabi, Amédé, Vinayachandran, Vinesh, Patel, Nisha A, Yen, Kuangyu, Reja, Rohit, Ebong, Ima‐O, Schoehn, Guy, Robinson, Carol V, Pugh, B Franklin, Panne, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931181/
https://www.ncbi.nlm.nih.gov/pubmed/27225933
http://dx.doi.org/10.15252/embj.201694105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931181/
https://www.ncbi.nlm.nih.gov/pubmed/27225933
http://dx.doi.org/10.15252/embj.201694105

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